Orthobiologics helps to heal injured muscles, fractures, tendons and ligaments more quickly. These are made up of naturally occurring body substances such as autologous conditioned serum, autologous blood, bone grafts, stem cells, platelet rich plasma, and growth factors. Therefore, these are commercially available for orthopedic applications such as joint reconstruction, spinal fusion, and sports related injuries.
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Rise in number of orthopedic surgeries, rapidly aging population, increasing in adoption of advanced products, and growing demand for minimal invasive procedures are set to drive the global market for orthobiologics. As per the report published by American Academy of Orthopedic Surgeons, in U.S., around 500,000 bone grafting surgeries are performed every year. Of these, almost half of the surgeries are related to spinal fusion. These large number of procedures lead to rise in demand for musculoskeletal tissue donation and a shortage of cadaver material.
Additionally, increased availability of products with high osteoinductive and osteoconductive properties will further contribute to the market growth. An osteoinductive protein provides biophysical stimulation which helps to repair and regenerate bone fractures. Moreover, the high demand for orthobiologics in orthopedic industry coupled with rise in adoption of orthobiologics in different orthopedic applications such as joint reconstruction, trauma, craniomaxillofacial, and spinal fusion.
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Development of novel products related to bone healing has changed the field of orthopedic treatment. Therefore, major players are highly focused on developing and commercializing technologically advanced products. For instance, in September 2015, Wright Medical Group Inc. obtained premarket approval for its Augment bone graft from FDA. This graft can be used in ankle or hind foot fusion procedures. Similarly, in November 2015, CeraPedics, an orthobiologics company, obtained Premarket Approval (PMA) application for its “i-FACTOR Peptide Enhanced Bone Graft”. This graft can be used for the treatment of degenerative cervical disc related disorders. Thus, introduction of technologically advanced products is set to propel the market growth.
Major players operating in this market are Medtronic plc, Stryker Corporation, Bone Biologics Corp., Orthofix, Inc., Arthrex, Inc., Isto Biologics, Bioventus, NuVasive, Inc., Osiris Therapeutics, Inc., and RTI Surgical, Inc. These companies are highly focused on expanding their geographical presence through establishing strong distribution channels and direct sales network.
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