An ampoule is a small sealed vial made up of glass or plastic containing solution or powder that is usually made into solution for intravenous and intramuscular injections. Ampoule is used to store pharmaceutical chemicals and biologics that must be protected from harmful air contaminants. These vials are hermetically sealed by making them airtight by melting top with open flame. Glass ampoules are more expensive as compared to plastic ampoules however they are extensively used in situations where blocking of gases and liquids is required to protect pharmaceutical solutions. Syringes are reciprocating pump consisting of piston integrated into cylindrical tube that is used to inject medications into the body. Syringes are frequently used to administer various clinical drugs and medicine into blood stream. Syringes are of different types such as disposable syringes, safety syringes, injection pens, specialty pumps and insulin pumps. Syringes specially designed to inject insulin into the body are shorter in length and effectively delivers insulin without rupturing blood vessels.
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Ampoules are widely used for packaging of sensitive clinical medications. Number of materials is used for manufacturing ampoule including plastic, glass and cyclic olefin copolymer. Cyclic olefin copolymer (COC) is relatively new class of polymer which is used in wide range of pharmaceutical packing applications such as packaging film, vials and ampoules. Benefits such as low moisture absorption rate, high transparency, BPA free, high heat resistance and minimum estrogenic activity make COC an ideal packaging material for pharmaceutical drugs. Whereas glass syringes are used to deliver drugs by connecting to other devices such as needles, needleless luer locks and other transfer units. Glass syringe are still widely preferred owing to lower level of contaminants due to low traces of metals and they can be used to store blood sample which can be used later for diagnosis.
Continuous advancements in biologics, rapid development of pharmaceutical sector, increasing prevalence of diseases and patent expiry of leading biologics which led to introduction of biosimilars globally, is expected to drive the growth of the market. Furthermore increasing awareness about safe clinical medicine delivery options such as pen needles and rise in adoption of safety needles will propel growth of the market. However high cost of special packaging required for sensitive medicines and increasing incidence of product breakage is expected to hamper growth of the market.
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Some of the major players operating in the global ampoule and syringe market include Vetter Pharma International GmbH, Nipro Corporation, Stevanato Group, TOPAS Advanced Polymers, Baxter International Inc., Unilife Corporation., Medtronic, Ypsomed Holding AG, Becton, Dickinson and Company., West Pharmaceutical Services Inc., and Zeon Corp. Major players are focusing on new product launch for effective drug delivery to patients. For instance, Terumo Corporation in Jan 2017 has launched new syringe known as PLAJEX polymer refillable syringes. This new container closure system is user friendly with easy grip twist off tip cap. Contact material for syringe is carefully selected to prevent breakage and leachables.
Pharmaceutical packaging market is rapidly evolving and has gone through changes in the past few decades. Market is expected to witness positive scenario in forthcoming years owing to continuous product up gradation impacting demand for syringes and ampoules. Although syringes and ampoules will remain in use, the market is rapidly moving towards prefillable syringes, pen systems and automatic injections. Many players are even focusing on designing customized delivery system to acquire more customers and ultimately larger market share.
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